Test the Effectiveness of Tegari Leaf Extract (Dianella nemorosa Lam.) from Papua on Burn Wound Healing in Rabbit (Oryctolagus cuniculus): Experimental Study
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Abstract
The tegari plant (Dianella nemorosa Lam.) known locally as "pra kepey" (Papua). D. nemorosa Lam. plant is one of the traditional medicines from Papua which is used as a medicine to heal external wounds such as cuts, burns, and internal wounds. The aim of this research was to test the effectiveness of tegari leaf extract and to test the concentration of tegari leaf extract from Papua which was used most effectively for healing burns in rabbits. Each rabbit's back was divided into 6 control treatments, that is normal control (no treatment), negative control (Vaseline album), positive control (conventional burn gel), and D. nemorosa Lam. extract with a concentration of 0.1%, 0.5%, and 1%. The rabbit's back was anesthetized using 2% lidocaine HCl subcutaneously and induced with an iron metal diameter of 2.2 cm and a thickness of 1 mm which was heated in a blue flame for 3 minutes and then placed on the rabbit's back for 5 seconds until a second degree (deep) burn was formed. The diameter of the rabbit's back burn wound was measured for 21 days. The results of the percentage of healing of burn wounds from D. nemorosa Lam. extract at concentrations of 0.1%, 0.5%, and 1%, respectively, were 76.80%, 79.00%, and 87.40% on day 21st. The data were analyzed using one-way ANOVA, namely in the form of the percentage of burn wound healing which showed that there were differences in the effect of burn wound healing in each control treatment group because the significant value was p=<0,00 (p=<0,05) indicating that there were significant differences between each group. D. nemorosa Lam. extract is effective in healing burns.
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